Blue Cross Blue Shield of Minnesota Medical Policy

 
 

Medical Policy:
II-163-008
Topic:
Infusion or Injection of Vitamins and/or Minerals
Section:
Medicine
Effective Date:
November 28, 2021
Issued Date:
November 28, 2021
Last Revision Date:
November 2021
Annual Review:
November 2021
 
 

This policy version was replaced November 28, 2022. To find the newest version, go to https://www.bluecrossmn.com/providers/medical-policy-and-utilization-management, read and accept the Blue Cross Medical Policy Statement, then select “Blue Cross and Blue Shield of Minnesota Medical Policies.” This will bring up the Medical Policy search screen. Enter the policy number without the version number (last 3 digits).

Vitamin or mineral deficits can occur in patients whose food intake has been restricted or when absorption of essential nutrients is impaired. In most cases, imbalances can be corrected through consuming a balanced diet along with oral supplementation of vitamins and/or minerals that are lacking. Infusion or injection of vitamins and/or minerals may be done when urgent supplementation is needed to treat or prevent a medical condition or when oral supplementation is contraindicated. In contrast to total parenteral nutrition, which contains vitamins, minerals, proteins, sugars, and fats, infusion or injection of vitamins and/or minerals is not a complete form of nutrition

This policy is designed to address medical guidelines that are appropriate for the majority of individuals with a particular disease, illness, or condition. Each person's unique clinical circumstances may warrant individual consideration, based on review of applicable medical records.

Policy Position Coverage is subject to the specific terms of the member's benefit plan.

Note: For iron infusion, see policy II-243, Intravenous Iron Replacement Therapy.

I.    Infusion or injection of vitamins and/or minerals may be considered MEDICALLY NECESSARY AND APPROPRIATE when BOTH of the following criteria are met:

  • The individual has been diagnosed with ONE of the following conditions:
    • A vitamin and/or mineral deficiency that has been confirmed by laboratory serum analysis; OR
    • A medical condition requiring acute treatment or prophylaxis in the presence of well-recognized sequelae with a vitamin and/or mineral including but not limited to the following:
      • Coagulopathy or reversal of anticoagulation
      • Alcohol withdrawal syndrome
      • Wernicke's encephalopathy
      • Refeeding syndrome
      • Anorexia nervosa or bulimia nervosa; 
  • AND
  • Oral administration is less effective, not feasible, or not appropriate.

II.   Infusion or injection of vitamins and/or minerals is considered EXPERIMENTAL/INVESTIGATIVE for all other indications not addressed by the criteria above, including but not limited to the following:

  • Nutritional supplementation in the absence of a vitamin and/or mineral deficiency
  • Disease prevention
  • Mental health disorders
  • Chronic fatigue syndrome
  • Fibromyalgia
  • Chronic Pain 
96360 96361 96365 96366 96367 96368





Denial Statements

No additional statements.



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Blue Cross and Blue Shield of Minnesota medical policies apply generally to all Blue Cross and Blue Plus plans and products. Benefit plans vary in coverage and some plans may not provide coverage for certain services addressed in the medical policies. When determining coverage, reference the member’s specific benefit plan, including exclusions and limitations.

Medicaid products may provide different coverage for certain services, which may be addressed in different policies. For Minnesota Health Care Program (MHCP) policies, please consult the MHCP Provider Manual website.

Medicare products may provide different coverage for certain services, which may be addressed in different policies. For Medicare National Coverage Determinations (NCD), Local Coverage Determinations (LCD), and/or Local Coverage Articles, please consult CMS, National Government Services, or CGS websites. 

Note that services with specific coverage criteria may be reviewed retrospectively to determine if criteria are being met. Retrospective denial of claims may result if criteria are not met.

Blue Cross and Blue Shield of Minnesota reserves the right to revise, update and/or add to its medical policies at any time without notice. Codes listed on this policy are included for informational purposes only and are subject to change without notice. Inclusion or exclusion of a code does not constitute or imply member coverage or provider reimbursement. 

These guidelines are the proprietary information of Blue Cross and Blue Shield of Minnesota. Any sale, copying or dissemination of the medical policies is prohibited; however, limited copying of medical policies is permitted for individual use.

Acknowledgements:

CPT® codes copyright American Medical Association® 2022. All rights reserved.

CDT codes copyright American Dental Association® 2022. All rights reserved.